Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 7/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.56 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.54 |
| ▸ | EGFR | P00533 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.48 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.45 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.45 |
| ▸ | FLT1 | P17948 | 2/20 | 0.45 |
| ▸ | FLT4 | P35916 | 2/20 | 0.45 |
| ▸ | KDR | P35968 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767482 | 0.92 | PTGS2 (0.58) | PTGS2PTGS1P4HTMEGFRGAA | |
| Hydrochloric Acid SCHEMBL8915942 | 0.91 | PTGS2 (0.56) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8915935 | 0.85 | PTGS2 (0.51) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8767487 | 0.82 | PTGS2 (0.55) | PTGS2PTGS1P4HTMEGFRGAA | |
| Hydrochloric Acid SCHEMBL9231980 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL9233289 | 0.81 | PTGS2 (0.54) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8874936 | 0.81 | PTGS2 (0.46) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8875058 | 0.78 | MEN1 (0.45) | PTGS2PTGS1P4HTMEGFRMCL1 | |
| SCHEMBL8869543 | 0.78 | P4HTM (0.76) | PTGS2PTGS1P4HTMEGFRALKBH2 | |
| SCHEMBL8097851 | 0.77 | LMNA (0.51) | GAAMEN1LMNAKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |