Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | AKT1 | P31749 | 4/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870497 | 0.94 | P4HTM (0.49) | PTPN1P4HTMCA1CA2GAA | |
| SCHEMBL8869114 | 0.92 | PTPN1 (0.51) | PTPN1P4HTMCA1CA2GAA | |
| SCHEMBL8868506 | 0.90 | P4HTM (0.51) | P4HTMCA1CA2GAAALDH1A1 | |
| SCHEMBL8870040 | 0.88 | L3MBTL1 (0.48) | P4HTMGAAALDH1A1MEN1KMT2A | |
| SCHEMBL9138327 | 0.88 | PTPN1 (0.52) | PTPN1P4HTMCA1CA2SMN1; SMN2 | |
| SCHEMBL7862852 | 0.87 | PTPN1 (0.47) | PTPN1CA1CA2GAASMN1; SMN2 | |
| SCHEMBL8869547 | 0.86 | CA2 (0.52) | P4HTMCA2ALDH1A1 | |
| SCHEMBL8868734 | 0.86 | L3MBTL1 (0.55) | P4HTMALDH1A1MEN1KMT2APKM | |
| SCHEMBL9138856 | 0.86 | P4HTM (0.60) | PTPN1P4HTMCA1CA2SMN1; SMN2 | |
| SCHEMBL8869116 | 0.86 | P4HTM (0.53) | P4HTMCA2ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |