Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.44 |
| ▸ | CA2 | P00918 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7862831 | 0.94 | PKM (0.41) | PTPN1CA1CA2MAPTALDH1A1 | |
| SCHEMBL7862667 | 0.92 | PTPN1 (0.47) | PTPN1CA1CA2SMN1; SMN2MAPT | |
| SCHEMBL7869445 | 0.90 | PKM (0.43) | CA1CA2ALDH1A1MEN1KMT2A | |
| SCHEMBL7862672 | 0.89 | L3MBTL1 (0.47) | SMN1; SMN2MAPTALDH1A1MEN1KMT2A | |
| SCHEMBL9018165 | 0.88 | PTPN1 (0.51) | PTPN1CA1CA2SMN1; SMN2MAPT | |
| SCHEMBL9574752 | 0.87 | L3MBTL1 (0.53) | ALDH1A1MEN1KMT2APKM | |
| SCHEMBL8869428 | 0.87 | PTPN1 (0.49) | PTPN1CA1CA2SMN1; SMN2MAPT | |
| SCHEMBL7862740 | 0.87 | ALDH1A1 (0.48) | CA1CA2SMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7869400 | 0.86 | CA12 (0.42) | PTPN1CA1CA2SMN1; SMN2MAPT | |
| SCHEMBL7862801 | 0.86 | CA2 (0.48) | CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0562512-B1 | Sulfonamidocarbonylpyridine-2-carboxamides and their use as medicines | HOECHST AG (DE) | 2001-02-21 | — | — | EP | disclosed |
| EP-0562512-A1 | Sulfonamido- and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicines | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-09-29 | — | — | EP | disclosed |