Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.46 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.46 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | BCL2 | P10415 | 1/20 | 0.43 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.43 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868734 | 0.95 | L3MBTL1 (0.55) | L3MBTL1P4HTMLMNAHDAC1HDAC2 | |
| SCHEMBL8868481 | 0.90 | HDAC3 (0.51) | P4HTMLMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL8868164 | 0.89 | L3MBTL1 (0.53) | L3MBTL1P4HTMLMNAHDAC3HDAC4 | |
| SCHEMBL7862672 | 0.89 | L3MBTL1 (0.47) | L3MBTL1LMNAHDAC3HDAC4HDAC1 | |
| SCHEMBL8869428 | 0.88 | PTPN1 (0.49) | P4HTMHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL8868861 | 0.88 | P4HTM (0.52) | P4HTMMEN1KMT2ANAMPTNPC1 | |
| SCHEMBL8867998 | 0.87 | P4HTM (0.51) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8870497 | 0.87 | P4HTM (0.49) | L3MBTL1P4HTMLMNAGAAALDH1A1 | |
| SCHEMBL8869119 | 0.86 | L3MBTL1 (0.56) | L3MBTL1P4HTMHDAC1HDAC2GAA | |
| SCHEMBL8869178 | 0.86 | P4HTM (0.54) | P4HTMLMNAALDH1A1PKMBDKRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |