Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | DRD1 | P21728 | 3/20 | 0.44 |
| ▸ | DRD5 | P21918 | 3/20 | 0.44 |
| ▸ | DRD3 | P35462 | 3/20 | 0.44 |
| ▸ | DRD4 | P21917 | 2/20 | 0.44 |
| ▸ | TYR | P14679 | 1/20 | 0.42 |
| ▸ | MIF | P14174 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA5A | P35218 | 1/20 | 0.42 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.42 |
| ▸ | KIT | P10721 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.41 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
| ▸ | LTA4H | P09960 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3274879 | 0.84 | ESR2 (0.52) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL30534978 | 0.84 | ESR2 (0.52) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL9143570 | 0.83 | CES2 (0.45) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL7511173 | 0.81 | MAOA (0.59) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL22650934 | 0.80 | CA2 (0.51) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL6611968 | 0.78 | CYP19A1 (0.38) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL8168164 | 0.77 | MAPKAPK2 (0.47) | DRD2DRD1DRD5DRD3DRD4 | |
| SCHEMBL31525565 | 0.76 | CA12 (0.54) | CA2CA5AALDH1A1MAPT | |
| SCHEMBL14495775 | 0.76 | CA12 (0.54) | CA2CA5AALDH1A1MAPT | |
| SCHEMBL7511142 | 0.75 | MAOA (0.65) | DRD2DRD1DRD5DRD3DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5623080-A | Fluorone and pyronin Y derivatives | SPECTRA GROUP LIMITED, INC. (US) | 1997-04-22 | — | — | US | disclosed |
| US-5451343-A | Photoinitiators | SPECTRA GROUP LIMITED, INC. (US) | 1995-09-19 | — | — | US | disclosed |
| WO-1995014689-A1 | FLUORONE AND PYRONIN Y DERIVATIVES | SPECTRA GROUP LIMITED, INC. (US) | 1995-06-01 | — | — | WO | disclosed |
| EP-0515133-A2 | Fluorone and pyronin Y derivatives | SPECTRA GROUP LIMITED INC (US) | 1992-11-25 | — | — | EP | disclosed |