Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8868915 | 0.90 | P4HTM (0.66) | P4HTMALDH1A1HPGD | |
| SCHEMBL8869176 | 0.89 | P4HTM (0.53) | P4HTMKDM4EALDH1A1HPGDPKM | |
| SCHEMBL8868481 | 0.89 | HDAC3 (0.51) | P4HTMKDM4ENPC1RAB9ABDKRB1 | |
| SCHEMBL8869962 | 0.89 | P4HTM (0.58) | P4HTMKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL8868425 | 0.88 | P4HTM (0.53) | P4HTMNPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL8868734 | 0.87 | L3MBTL1 (0.55) | P4HTMALDH1A1LMNAPKM | |
| SCHEMBL8868506 | 0.87 | P4HTM (0.51) | P4HTMKDM4EALDH1A1BDKRB1HPGD | |
| SCHEMBL8869822 | 0.86 | P4HTM (0.54) | P4HTMNPC1ALDH1A1RAB9ALMNA | |
| SCHEMBL8870069 | 0.86 | P4HTM (0.57) | P4HTMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7862839 | 0.86 | SMN1; SMN2 (0.48) | P4HTMKDM4EALDH1A1BDKRB1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607954-A | Sulfonamido- and sulfonamidocarbonylpyridine-2-carboxamides and their pyridine-n-oxides, process for their preparation and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |