SCHEMBL8870484

SCHEMBL8870484

NS(=O)(=O)c1ccc(S(=O)(=O)Cl)s1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
CA2 P00918 19/20 0.52
CA1 P00915 7/20 0.42
CA12 O43570 6/20 0.42
CA9 Q16790 6/20 0.42
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
L3MBTL1 Q9Y468 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7132351 0.87 L3MBTL1 (0.46) CA2L3MBTL1
SCHEMBL185767 0.76 PTGES2 (0.53) CA2CA1CA12CA9L3MBTL1
SCHEMBL15880558 0.76 LOX (0.48) CA2L3MBTL1
SCHEMBL4802533 0.75 CA2 (0.53) CA2CA1CA12CA9CA4
Hydrochloric Acid SCHEMBL185389 0.74 PTGES2 (0.51) CA2CA1CA12CA9L3MBTL1
SCHEMBL5153269 0.73 CA2 (0.48) CA2CA1CA12CA9CA4
SCHEMBL19269 0.73 KMT2A (0.46) L3MBTL1
SCHEMBL25218047 0.71 DAO (0.37) L3MBTL1
SCHEMBL9996004 0.71 L3MBTL1 (0.33) L3MBTL1
SCHEMBL16732 0.71 KMT2A (0.50) L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4573088-A1 HETEROCYCLE RBM39 MODULATORS Recursion Pharmaceuticals, Inc. (US) 2025-06-25 EP disclosed
CN-119630658-A Heterocyclic RBM39 modulators 递归医药公司 2025-03-14 CN disclosed
US-20240092770-A1 Heterocycle RMB39 Modulators RECURSION PHARMACEUTICALS, INC. 2024-03-21 US disclosed
WO-2024039689-A1 HETEROCYCLE RBM39 MODULATORS RECURSION PHARMACEUTICALS, INC. (US) 2024-02-22 WO disclosed
WO-2022076383-A1 SULFONANILIDE AND BENZYLSULFONYL DERIVATIVES, AND COMPOSITIONS AND METHODS THEREOF Lysoway Therapeutics, Inc. (US) 2022-04-14 WO disclosed
US-5679670-A CONTROLLING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1997-10-21 US disclosed
US-5585377-A CONTROLLING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1996-12-17 US disclosed
US-5378703-A FOR CONTROLLING INTRAOCULAR PRESSURE ALCON LABORATORIES, INC. (US) 1995-01-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240092770-A1 Heterocycle RMB39 Modulators PRMT9, RCC2, RBBP9 CA2 4825/4885CA1 4867/4885CA12 4692/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.