Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9250150 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL8870492 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL3826056 | 1.00 | KDM4E (0.46) | KDM4EALDH1A1POLBGAARAB9A | |
| SCHEMBL9264341 | 0.90 | GPR119 (0.42) | KDM4EALDH1A1GPR119 | |
| SCHEMBL9645053 | 0.90 | GPR119 (0.42) | KDM4EALDH1A1GPR119 | |
| SCHEMBL9271459 | 0.89 | ALDH1A1 (0.45) | KDM4EALDH1A1POLBGPR119 | |
| SCHEMBL14024616 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL6185805 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL3072035 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 | |
| SCHEMBL13091656 | 0.87 | HSD17B10 (0.54) | ALDH1A1POLBGAARAB9AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2099778-A2 | AMIDO ANTI-VIRAL COMPOUNDS | Smithkline Beecham Corporation (US) | 2009-09-16 | — | — | EP | disclosed |
| US-20080181866-A1 | Amido Anti-viral Compounds | GENELABS TECHNOLOGIES, INC. | 2008-07-31 | — | — | US | disclosed |
| WO-2008064218-A2 | AMIDO ANTI-VIRAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-05-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080181866-A1 | Amido Anti-viral Compounds | ZC3HAV1, U2SURP, ZC3HAV1L | KDM4E 2989/4885ALDH1A1 4630/4885POLB 1374/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.