Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870492 | 0.90 | KDM4E (0.46) | GPR119ALDH1A1KDM4E | |
| SCHEMBL3826056 | 0.90 | KDM4E (0.46) | GPR119ALDH1A1KDM4E | |
| SCHEMBL9250150 | 0.90 | KDM4E (0.46) | GPR119ALDH1A1KDM4E | |
| SCHEMBL3827938 | 0.90 | KDM4E (0.46) | GPR119ALDH1A1KDM4E | |
| SCHEMBL9645053 | 0.89 | GPR119 (0.42) | GPR119ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9271459 | 0.88 | ALDH1A1 (0.45) | GPR119ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9738504 | 0.85 | GPR119 (0.44) | GPR119ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9738499 | 0.85 | ALDH1A1 (0.44) | GPR119ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9819881 | 0.84 | GPR119 (0.47) | GPR119ALDH1A1KDM4EMEN1MAPT | |
| SCHEMBL9647713 | 0.84 | GPR119 (0.38) | GPR119ALDH1A1KDM4EMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5382670-A | Platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1995-01-17 | — | — | US | disclosed |
| EP-0574494-A4 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LAB (US) | 1994-07-06 | — | — | EP | disclosed |
| EP-0591333-A1 | AZANORBORNANE DERIVATIVES. | PFIZER (US) | 1994-04-13 | — | — | EP | disclosed |
| EP-0574494-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1993-12-22 | — | — | EP | disclosed |
| WO-1992014732-A1 | INDOLES USEFUL AS PLATELET ACTIVATING FACTOR ANTAGONISTS | ABBOTT LABORATORIES (US) | 1992-09-03 | — | — | WO | disclosed |
| EP-0499987-A1 | Platelet activating factor antagonists | ABBOTT LABORATORIES (US) | 1992-08-26 | — | — | EP | disclosed |
| US-5120749-A | Treatment of anaphylactic shock, respiratory distress syndrome, acute inflammation, delayed cellulosr immunity, parturtition, fetal lung maturation, and cellular differentiation | ABBOTT LABORATORIES (US) | 1992-06-09 | — | — | US | disclosed |