Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR55 | Q9Y2T6 | 2/20 | 0.64 |
| ▸ | MAOA | P21397 | 1/20 | 0.61 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA2 | P00918 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | CA3 | P07451 | 1/20 | 0.55 |
| ▸ | CA6 | P23280 | 1/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA7 | P43166 | 1/20 | 0.55 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | ACHE | P22303 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11620610 | 0.82 | GPR55 (0.67) | GPR55MAOAADAM17MMP2MMP9 | |
| SCHEMBL10419623 | 0.79 | MAOA (0.57) | GPR55MAOAADAM17MMP2MMP9 | |
| SCHEMBL8871071 | 0.79 | MAOA (0.57) | MAOAKDM4EALDH1A1CA12CA1 | |
| SCHEMBL15065807 | 0.77 | MAOB (0.56) | MAOAADAM17MMP2MMP9KDM4E | |
| SCHEMBL12839872 | 0.75 | MAOB (0.64) | GPR55KDM4EALDH1A1CA12CA1 | |
| SCHEMBL9057890 | 0.74 | CA2 (0.64) | GPR55ADAM17MMP2MMP9KDM4E | |
| SCHEMBL11405408 | 0.74 | CA2 (0.64) | GPR55KDM4EALDH1A1CA12CA1 | |
| SCHEMBL28315404 | 0.74 | MAOB (0.62) | GPR55KDM4EALDH1A1CA12CA1 | |
| SCHEMBL2432666 | 0.74 | KDM4E (0.66) | GPR55KDM4EALDH1A1CA12CA1 | |
| SCHEMBL12523188 | 0.73 | GPR55 (0.70) | GPR55MAOAKDM4EALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607928-A | Carbapenem derivatives containing a bicyclic ketone substituent and their use as anti-infectives | ZENECA LIMITED (GB) | 1997-03-04 | — | — | US | disclosed |
| EP-0695753-A1 | Carbapenem derivatives containing a bicyclic substituent, process for their preparation, and their use | ZENECA LIMITED (GB) | 1996-02-07 | — | — | EP | disclosed |