Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | PDE7A | Q13946 | 6/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.38 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.38 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.38 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | CCR2 | P41597 | 3/20 | 0.38 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15329508 | 0.79 | TSHR (0.43) | TSHRMAPK1PDE7APOLBLMNA | |
| SCHEMBL3610741 | 0.78 | TSHR (0.58) | TSHRMAPK1POLBLMNAALDH1A1 | |
| SCHEMBL32682192 | 0.78 | TSHR (0.58) | TSHRMAPK1POLBLMNAALDH1A1 | |
| SCHEMBL27426321 | 0.77 | TSHR (0.46) | TSHRMAPK1POLBLMNAALDH1A1 | |
| SCHEMBL30153092 | 0.74 | ALDH1A1 (0.45) | TSHRMAPK1POLBLMNAALDH1A1 | |
| SCHEMBL11429558 | 0.73 | PDE7A (0.52) | TSHRMAPK1PDE7APOLBLMNA | |
| SCHEMBL30867127 | 0.72 | TSHR (0.54) | TSHRMAPK1POLBGLAGAA | |
| SCHEMBL203703 | 0.72 | ALDH1A1 (0.51) | TSHRMAPK1PDE7ALMNAALDH1A1 | |
| SCHEMBL29189985 | 0.72 | ALDH1A1 (0.50) | TSHRMAPK1POLBLMNAALDH1A1 | |
| SCHEMBL2653845 | 0.72 | CCR2 (0.55) | TSHRMAPK1PDE7ALMNAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5612483-A | AMINATION | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-18 | — | — | US | disclosed |