Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | GRM5 | P41594 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8870879 | 1.00 | GPR119 (0.46) | GPR119FFAR2MAOBABCB1GRM5 | |
| SCHEMBL21094108 | 0.91 | GPR119 (0.46) | GPR119MAOBABCB1GRM5NPSR1 | |
| SCHEMBL28534291 | 0.88 | GPR119 (0.44) | GPR119MAOBABCB1GRM5NPSR1 | |
| SCHEMBL29040317 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL475745 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL30720983 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL6183606 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL2896922 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL859599 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 | |
| SCHEMBL5156869 | 0.87 | FFAR2 (0.51) | GPR119FFAR2ABCB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610144-A | CHOLECYSTOKININ OR GASTRIN ANTAGONISTS; NERVOUS SYSTEM AND GASTROINTESTINAL DISORDERS | RHONE-POULENC RORER S.A. (FR) | 1997-03-11 | — | — | US | disclosed |