Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 5/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | AOC1 | P19801 | 2/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21094108 | 0.91 | GPR119 (0.46) | GPR119MAOBMAOAAOC1GRM5 | |
| SCHEMBL8870879 | 0.88 | GPR119 (0.46) | GPR119MAOBGRM5NPSR1MAPT | |
| SCHEMBL8870873 | 0.88 | GPR119 (0.46) | GPR119MAOBGRM5NPSR1MAPT | |
| SCHEMBL28520946 | 0.88 | FFAR2 (0.45) | MAOBMAOAGRM5MAPTABCB1 | |
| SCHEMBL28523802 | 0.88 | RIPK1 (0.48) | GPR119MAOBMAOAGRM5 | |
| SCHEMBL28534271 | 0.87 | ABCB1 (0.44) | GPR119ABCB1 | |
| SCHEMBL20835473 | 0.84 | GPR119 (0.43) | GPR119GRM5NPSR1MAPTABCB1 | |
| SCHEMBL20835862 | 0.83 | MAOB (0.41) | MAOBMAOAAOC1 | |
| SCHEMBL21094084 | 0.83 | FFAR2 (0.42) | GPR119ABCB1 | |
| SCHEMBL28528400 | 0.83 | GPR119 (0.41) | GPR119MAOBMAOAGRM5NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109476639-B | Pyrrolidine derivatives | 橘生药品工业股份有限公司 | 2021-02-26 | — | — | CN | disclosed |