Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.51 |
| ▸ | ELANE | P08246 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | CNR2 | P34972 | 2/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 2/20 | 0.41 |
| ▸ | CTSG | P08311 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9123537 | 0.84 | KMT2A (0.39) | KMT2AELANEALDH1A1MCL1F2 | |
| SCHEMBL9120480 | 0.71 | F2 (0.45) | KMT2AALDH1A1F2MEN1LMNA | |
| SCHEMBL9122197 | 0.69 | GRIA4 (0.33) | GRIA4 | |
| SCHEMBL2180036 | 0.66 | CES2 (0.67) | KMT2AHPGDMEN1LMNAMAPT | |
| SCHEMBL7896809 | 0.66 | CES2 (0.59) | ALDH1A1HPGDMAPTNPSR1CES2 | |
| SCHEMBL3469060 | 0.65 | VNN1 (0.63) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL26487595 | 0.65 | GPR183 (0.73) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL9121603 | 0.65 | GRIA4 (0.41) | KMT2AALDH1A1LMNAMAPTMAPK1 | |
| SCHEMBL11387722 | 0.65 | CHRNB2 (0.50) | KMT2AALDH1A1HPGDMEN1LMNA | |
| SCHEMBL20631562 | 0.64 | HPGD (0.86) | KMT2AALDH1A1HPGDMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5702681-A | ADMINISTERING A NITROPYRROLE OR A PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-12-30 | — | — | US | disclosed |
| US-5665759-A | ADMINISTERING A NITROPYRROLE OR PYRROLE CARBONITRILE COMPOUND | AMERICAN CYANAMID COMPANY (US) | 1997-09-09 | — | — | US | disclosed |
| EP-0372263-B1 | Pyrrole carbonitrile and nitro-pyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID CO (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0557732-A1 | Methods and compositions for protecting animals against attack and infestation by helminth, acarid and anthropod endo- and ectoparasites | AMERICAN CYANAMID COMPANY (US) | 1993-09-01 | — | — | EP | disclosed |
| US-5204332-A | PYRROLE CARBONITRILE AND NITROPYRROLE INSECTICIDAL AND ACARICIDAL AND MOLLUSCICIDAL AGENTS | AMERICAN CYANAMID COMPANY (US) | 1993-04-20 | — | — | US | disclosed |
| US-5162308-A | Pyrrole carbonitrile and nitropyrrole insecticidal, acaricidal and molluscicidal agents and methods for the preparation thereof | AMERICAN CYANAMID COMPANY (US) | 1992-11-10 | — | — | US | disclosed |