Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 7/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | TSHR | P16473 | 6/20 | 0.51 |
| ▸ | USP2 | O75604 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | KCNN3 | Q9UGI6 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8871279 | 0.81 | ALDH1A1 (0.58) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL31201486 | 0.79 | L3MBTL1 (0.54) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL28223231 | 0.78 | ALDH1A1 (0.54) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL8871084 | 0.78 | MAPT (0.43) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL34462910 | 0.77 | CYP1A2 (0.60) | ALDH1A1MAPTMEN1KMT2AGAA | |
| SCHEMBL13351975 | 0.75 | NPC1 (0.52) | ALDH1A1CLK4NPC1SMN1; SMN2POLB | |
| SCHEMBL1373630 | 0.74 | CYP1A2 (0.56) | ALDH1A1MAPTHPGDMEN1KMT2A | |
| SCHEMBL5545750 | 0.74 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1MAPTHPGDGAA | |
| SCHEMBL5626734 | 0.74 | L3MBTL1 (0.67) | L3MBTL1ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL1373028 | 0.74 | CYP1A2 (0.50) | ALDH1A1MAPTHPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1154636-C | Process for preparing intermediate in preparation of substd. peperidines | �����ɷ� | 2004-06-23 | — | — | CN | disclosed |
| CN-1183408-A | Process for preparing intermediate in preparation of substd. peperidines | PFIZER (US) | 1998-06-03 | — | — | CN | disclosed |
| CN-1037768-C | Preparation of substituted piperidines | PFIZER (US) | 1998-03-18 | — | — | CN | disclosed |
| US-5663349-A | Preparation of substituted piperidenes | PFIZER INC (US) | 1997-09-02 | — | — | US | disclosed |
| EP-0532515-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-10-23 | — | — | EP | disclosed |
| EP-0619806-B1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER (US) | 1996-01-03 | — | — | EP | disclosed |
| US-5364943-A | Preparation of substituted piperidines | PFIZER INC. (US) | 1994-11-15 | — | — | US | disclosed |
| EP-0619806-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES. | PFIZER (US) | 1994-10-19 | — | — | EP | disclosed |
| WO-1993011110-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1993-06-10 | — | — | WO | disclosed |
| EP-0532515-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES. | PFIZER (US) | 1993-03-24 | — | — | EP | disclosed |
| WO-1991018878-A1 | PREPARATION OF SUBSTITUTED PIPERIDINES | PFIZER INC. (US) | 1991-12-12 | — | — | WO | disclosed |