Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 8/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 8/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 8/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 8/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.50 |
| ▸ | CLK4 | Q9HAZ1 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 4/20 | 0.50 |
| ▸ | USP2 | O75604 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 7/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22625722 | 0.80 | CASP6 (0.43) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL27874525 | 0.80 | MEN1 (0.47) | CYP1A2CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL1373630 | 0.80 | CYP1A2 (0.56) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL26082834 | 0.78 | CASP6 (0.41) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL1376602 | 0.78 | KDM4E (0.59) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL28085556 | 0.77 | NPC1 (0.62) | CLK4ALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL2560554 | 0.77 | CYP1A2 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL29957028 | 0.76 | EGFR (0.50) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL8872302 | 0.74 | L3MBTL1 (0.58) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 | |
| SCHEMBL23426225 | 0.74 | TRIM24 (0.47) | CYP1A2CYP3A4CYP2D6CYP2C19HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2394995-B1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2014-01-15 | — | — | EP | disclosed |
| US-8334236-B2 | Ring-fused 2-pyridone derivatives and herbicides | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 2012-12-18 | — | — | US | disclosed |
| EP-2394995-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | Kumiai Chemical Industry CO., LTD. (JP) | 2011-12-14 | — | — | EP | disclosed |
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2011-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110287937-A1 | RING-FUSED 2-PYRIDONE DERIVATIVES AND HERBICIDES | CBR3, CBR1, CHRM1 | CYP1A2 18/4885CYP3A4 53/4885CYP2D6 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.