⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9606508 | 0.79 | XDH (0.41) | — | |
| SCHEMBL10651306 | 0.76 | — | — | |
| SCHEMBL8040576 | 0.74 | — | — | |
| SCHEMBL2050612 | 0.72 | — | — | |
| SCHEMBL4805813 | 0.70 | XDH (0.35) | — | |
| SCHEMBL10618046 | 0.70 | CYP1A2 (0.36) | — | |
| SCHEMBL9688626 | 0.70 | XDH (0.48) | — | |
| SCHEMBL20819307 | 0.70 | XDH (0.35) | — | |
| SCHEMBL11803991 | 0.70 | ALDH1A1 (0.35) | — | |
| SCHEMBL10822233 | 0.70 | XDH (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5248776-A | Multistage reaction with sulfiding, cyclization and oxidative cleavage | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-09-28 | — | — | US | claimed |
| WO-1992010496-A1 | ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-06-25 | — | — | WO | claimed |
| JP-1083072-A | — | — | None | — | — | JP | disclosed |
| US-20230357767-A1 | NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE | BONAC CORPORATION (JP) | 2023-11-09 | — | — | US | disclosed |
| EP-4206325-A1 | NOVEL NUCLEIC ACID MOLECULE INHIBITING EXPRESSION OF TARGET GENE | BONAC CORPORATION (JP) | 2023-07-05 | — | — | EP | disclosed |
| US-20230183283-A1 | NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR | BONAC CORPORATION (JP) | 2023-06-15 | — | — | US | disclosed |
| EP-3527578-A1 | NOVEL GLYCOSIDE COMPOUND AND PRODUCTION METHOD THEREFOR | Bonac Corporation (JP) | 2019-08-21 | — | — | EP | disclosed |
| US-10377788-B2 | Method for producing glycoside compounds | BONAC CORPORATION (JP) | 2019-08-13 | — | — | US | disclosed |
| EP-2696681-B1 | 2'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-2697242-B1 | 2'-AZIDO SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME (US) | 2018-10-03 | — | — | EP | disclosed |
| EP-3301103-A1 | METHOD FOR PRODUCING GLYCOSIDE COMPOUNDS | BONAC CORPORATION (JP) | 2018-04-04 | — | — | EP | disclosed |
| WO-1998039353-A1 | IMPROVED CHIMERIC OLIGONUCLEOTIDE VECTORS | THE PERKIN-ELMER CORPORATION (US) | 1998-09-11 | — | — | WO | disclosed |
| US-5750343-A | Methods of detecting nucleic acids with nucleotide probes containing 4'-substituted nucleotides and kits therefor | SYNTEX INC. (US) | 1998-05-12 | — | — | US | disclosed |
| US-5446137-A | Substituent selected from linking group containing modifiers such as biotin, reactive groups, nucleic acids, catalysts, DNA intercalators, minor groove binders, clevage agents, and detectable labels | SYNTEX (U.S.A.) INC. (US) | 1995-08-29 | — | — | US | disclosed |
| US-5248776-A | Multistage reaction with sulfiding, cyclization and oxidative cleavage | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1993-09-28 | — | — | US | disclosed |
| WO-1992010496-A1 | ENANTIOMERICALLY PURE β-L-(-)-1,3-OXATHIOLANE NUCLEOSIDES | UNIVERSITY OF GEORGIA RESEARCH FOUNDATION, INC. (US) | 1992-06-25 | — | — | WO | disclosed |
| JP-S6483072-A | PRODUCTION OF 5-ALKYLPYRIMIDINE DERIVATIVE | UKI GOSEI KOGYO CO LTD | 1989-03-28 | — | — | JP | disclosed |
| WO-1986000067-A1 | PYRIMIDINES | THE SECRETARY OF STATE FOR DEFENCE IN HER BRITANNI (GB) | 1986-01-03 | — | — | WO | disclosed |
| US-4020073-A | Process for O-acylating thallus salts of 2-pyridone | TAYLOR EDWARD C | 1977-04-26 | — | — | US | disclosed |
| US-3947488-A | O-Acylation using organothallium compounds | TAYLOR EDWARD C | 1976-03-30 | — | — | US | disclosed |