SCHEMBL9606508

SCHEMBL9606508

C=CCc1cncc(CC=C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
XDH P47989 1/20 0.41
ALDH1A1 P00352 5/20 0.40
GABRA1 P14867 4/20 0.40
GABRB2 P47870 4/20 0.40
MAPT P10636 3/20 0.40
PPARG P37231 2/20 0.40
PPARD Q03181 2/20 0.40
MEN1 O00255 2/20 0.40
GAA P10253 2/20 0.40
CNR1 P21554 2/20 0.40
CNR2 P34972 2/20 0.40
KMT2A Q03164 2/20 0.40
KDM4E B2RXH2 1/20 0.40
ALDH2 P05091 1/20 0.40
AKR1B1 P15121 1/20 0.40
HPGD P15428 1/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PPARA Q07869 1/20 0.38
CYP3A4 P08684 4/20 0.37
SMN1; SMN2 Q16637 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20819307 0.89 XDH (0.35) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL24081239 0.87 DHFR (0.36) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL4805813 0.84 XDH (0.35) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL11803991 0.84 ALDH1A1 (0.35) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL9688626 0.84 XDH (0.48) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL215399 0.80 XDH (0.50) XDHALDH1A1GABRA1GABRB2MAPT
SCHEMBL887237 0.79
SCHEMBL20819331 0.78 CYP2C9 (0.37) XDHALDH1A1GAAKDM4EHPGD
SCHEMBL24460763 0.75 NOS3 (0.40) ALDH1A1PPARGPPARDCNR2PPARA
SCHEMBL1245519 0.72 XDH (0.44) XDHALDH1A1GABRA1GABRB2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4429131-A Process for the production of 3,5-dialkylpyridines LONZA LTD. (CH) 1984-01-31 US claimed
CN-116574050-A Method for producing structure-directing agents 庄信万丰股份有限公司 2023-08-11 CN disclosed
US-5202465-A PREPARATION OF 2-METHYLENEPROPANE-1,3-DIOL DICARBOXYLATES BASF AKTIENGESELLSCHAFT (DE) 1993-04-13 US disclosed
EP-0070012-B1 PROCESS FOR PREPARING 3,5-DIALKYL PYRIDINES LONZA AG (CH) 1987-10-21 EP disclosed
EP-0070012-B1 PROCESS FOR PREPARING 3,5-DIALKYL PYRIDINES LONZA AG (CH) 1987-10-21 EP disclosed
US-4429131-A Process for the production of 3,5-dialkylpyridines LONZA LTD. (CH) 1984-01-31 US disclosed
US-4429131-A Process for the production of 3,5-dialkylpyridines LONZA LTD. (CH) 1984-01-31 US disclosed
US-4429131-A Process for the production of 3,5-dialkylpyridines LONZA LTD. (CH) 1984-01-31 US disclosed
EP-0070012-A2 Process for preparing 3,5-dialkyl pyridines LONZA AG (CH) 1983-01-19 EP disclosed
EP-0070012-A2 Process for preparing 3,5-dialkyl pyridines LONZA AG (CH) 1983-01-19 EP disclosed