SCHEMBL887277

SCHEMBL887277

O=P1(O)Oc2ccccc2-c2ccccc2O1

nearest known ligand 0.52

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 14/20 0.52
MEN1 O00255 3/20 0.41
KMT2A Q03164 3/20 0.41
KDM4E B2RXH2 3/20 0.41
RECQL P46063 1/20 0.39
HSP90AA1 P07900 1/20 0.38
PKM P14618 1/20 0.35
TSHR P16473 1/20 0.35
ALOX15 P16050 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPK1 P28482 1/20 0.34
ATM Q13315 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426151 1.00 GPR84 (0.52) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL27539091 0.90 GPR84 (0.57) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL29415555 0.90 GPR84 (0.57) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL5804639 0.90 GPR84 (0.57) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL14525424 0.89 GPR84 (0.47) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL9308176 0.84 GPR84 (0.56) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL4103873 0.80 GPR84 (0.48) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL28372852 0.80 GPR84 (0.44) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL28420768 0.80 GPR84 (0.41) GPR84MEN1KMT2AKDM4ERECQL
SCHEMBL29519147 0.79 GPR84 (0.35) GPR84MEN1KMT2AKDM4EHSP90AA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2001019792-A1 COVALENTLY LINKED DIMERIC DNA BINDING MOLECULES GENELABS TECHNOLOGIES, INC. (US) 2001-03-22 WO claimed
WO-1989005794-A1 NOVEL ANTIARRHYTHMIC AGENTS I Aktiebolaget Hässle (SE) 1989-06-29 WO claimed
EP-0322390-A2 Novel antiarrhythmic agents I Aktiebolaget Hässle (SE) 1989-06-28 EP claimed
US-20240066509-A1 CHIRAL PHOSPHORIC ACIDS IMMOBILIZED ON SOLID SUPPORT FOR THE SELECTIVE PROTECTION OF HYDROXYL GROUPS REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-02-29 US disclosed
US-20240066509-A1 CHIRAL PHOSPHORIC ACIDS IMMOBILIZED ON SOLID SUPPORT FOR THE SELECTIVE PROTECTION OF HYDROXYL GROUPS REGENTS OF THE UNIVERSITY OF MICHIGAN 2024-02-29 US disclosed
WO-2023094526-A1 PREPARATION PROCESS OF P(=O)-HETEROATOM DERIVATIVES OF DIBENZOOXAPHOSPHACYCLES AIMPLAS ASOCIACIÓN DE INVESTIGACIÓN DE MATERIALES PLÁSTICOS Y CONEXAS (ES) 2023-06-01 WO disclosed
EP-4186912-A1 PREPARATION PROCESS OF P(=O)-HETEROATOM DERIVATIVES OF DIBENZOOXAPHOSPHACYCLES AIMPLAS - Asociación de Investigación de Materiales Plásticos y Conexas (ES) 2023-05-31 EP disclosed
EP-3541776-B1 NOVEL PROCESS FOR THE MANUFACTURE OF GAMMA, DELTA-UNSATURATED KETONES DSM IP ASSETS BV (NL) 2020-12-23 EP disclosed
EP-3541776-B1 NOVEL PROCESS FOR THE MANUFACTURE OF GAMMA, DELTA-UNSATURATED KETONES DSM IP ASSETS BV (NL) 2020-12-23 EP disclosed
WO-2020007342-A1 APPLICATION OF BIPHENYL PHOSPHATE COMPOUND AS GPR84 ANTAGONIST 中国科学院上海药物研究所 2020-01-09 WO disclosed
EP-3541776-A1 NOVEL PROCESS FOR THE MANUFACTURE OF GAMMA, DELTA-UNSATURATED KETONES DSM IP Assets B.V. (NL) 2019-09-25 EP disclosed
US-7902207-B2 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed
US-7902207-B2 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed
US-20070142639-A1 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
US-20070142639-A1 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2007-06-21 US disclosed
WO-2001019792-A1 COVALENTLY LINKED DIMERIC DNA BINDING MOLECULES GENELABS TECHNOLOGIES, INC. (US) 2001-03-22 WO disclosed
EP-0322390-B1 NOVEL ANTIARRHYTHMIC AGENTS I Aktiebolaget Hässle (SE) 1992-11-11 EP disclosed
US-5155133-A Antiarrhythmic compounds and pharmaceutical compositions and methods thereof AKTIEBOLAGET HASSLE (SE) 1992-10-13 US disclosed
WO-1989005794-A1 NOVEL ANTIARRHYTHMIC AGENTS I Aktiebolaget Hässle (SE) 1989-06-29 WO disclosed
EP-0322390-A2 Novel antiarrhythmic agents I Aktiebolaget Hässle (SE) 1989-06-28 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240066509-A1 CHIRAL PHOSPHORIC ACIDS IMMOBILIZED ON SOLID SUPPORT FOR THE SELECTIVE PROTECTION OF HYDROXYL GROUPS PYGL, PSPH, HAO2 GPR84 852/4885MEN1 4402/4885KMT2A 1501/4885
US-20070142639-A1 Process for production of amines SMS, CCNT1, PEAK1 GPR84 2711/4885MEN1 194/4885KMT2A 2635/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.