Pivalate

Pivalate

SCHEMBL8873099

CC(C)(C)C(=O)O.CCCCCCCC[N+](CCCCCCCC)(CCCCCCCC)CCCCCCCC

nearest known ligand 0.59

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A1 O15245 3/20 0.59
ALDH1A1 P00352 2/20 0.56
TSHR P16473 2/20 0.56
TP53 P04637 1/20 0.56
CYP3A4 P08684 1/20 0.56
ALOX15 P16050 1/20 0.56
ALOX12 P18054 1/20 0.56
SMN1; SMN2 Q16637 1/20 0.56
HIF1A Q16665 1/20 0.56
HSD17B10 Q99714 1/20 0.56
SLC22A2 O15244 1/20 0.55
DNM1 Q05193 4/20 0.52
GPR84 Q9NQS5 2/20 0.44
PPARG P37231 2/20 0.44
PPARD Q03181 2/20 0.44
PPARA Q07869 2/20 0.44
SLC22A6 Q4U2R8 1/20 0.44
SLC22A8 Q8TCC7 1/20 0.44
TLR2 O60603 1/20 0.44
HDAC11 Q96DB2 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetrabuthylammonium SCHEMBL2354515 0.93 SLC22A1 (0.57) SLC22A1ALDH1A1TSHRTP53CYP3A4
Octane SCHEMBL29057202 0.88 GPR84 (0.55) ALDH1A1TSHRALOX15HSD17B10GPR84
Pivalate SCHEMBL5570536 0.87 DNM1 (0.62) SLC22A1TSHRSMN1; SMN2HSD17B10DNM1
Pivalate SCHEMBL5573308 0.87 DNM1 (0.62) SLC22A1TSHRSMN1; SMN2HSD17B10DNM1
Pivalate SCHEMBL5574424 0.87 DNM1 (0.62) SLC22A1TSHRSMN1; SMN2HSD17B10DNM1
Pivalate SCHEMBL5571684 0.87 DNM1 (0.44) SLC22A1ALDH1A1TSHRALOX15HSD17B10
Pivalate SCHEMBL5571705 0.87 DNM1 (0.44) SLC22A1ALDH1A1TSHRALOX15HSD17B10
Pivalate SCHEMBL5575060 0.87 DNM1 (0.62) SLC22A1TSHRSMN1; SMN2HSD17B10DNM1
Pivalate SCHEMBL5570490 0.87 DNM1 (0.44) SLC22A1ALDH1A1TSHRALOX15HSD17B10
Pivalate SCHEMBL5574163 0.87 DNM1 (0.44) SLC22A1ALDH1A1TSHRALOX15HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5691440-A Catalyst and process for producing isocyanate trimers ARCO CHEMICAL TECHNONOGY, L.P. (US) 1997-11-25 US claimed
US-5691440-A Catalyst and process for producing isocyanate trimers ARCO CHEMICAL TECHNONOGY, L.P. (US) 1997-11-25 US disclosed