Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGA4 | P13612 | 1/20 | 0.52 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.52 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8873376 | 1.00 | ITGA4 (0.52) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL180029 | 0.88 | NPC1 (0.49) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL180028 | 0.88 | NPC1 (0.49) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL28690909 | 0.88 | KMT2A (0.47) | ALDH1A1L3MBTL1RAB9ANPC1TP53 | |
| SCHEMBL5968987 | 0.88 | KMT2A (0.47) | ALDH1A1L3MBTL1RAB9ANPC1TP53 | |
| SCHEMBL8874777 | 0.87 | CTSL (0.47) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL8874785 | 0.87 | CTSL (0.47) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL8873243 | 0.83 | TDP1 (0.41) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL8873229 | 0.83 | TDP1 (0.41) | ITGA4ITGB7P2RX7ALDH1A1L3MBTL1 | |
| SCHEMBL29562229 | 0.81 | KMT2A (0.47) | ALDH1A1L3MBTL1RAB9ANPC1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5683997-A | MODULATION OF AT2 RECEPTOR | CIBA-GEIGY CORPORATION (US) | 1997-11-04 | — | — | US | disclosed |
| US-5610153-A | ENZYME INHIBITORS; TREATMENT OF VASCULAR PROLIFERATION DISORDERS, STERILITY DYSFUNCTION, DYSMENORRHEA | CIBA-GEIGY CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |