Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 3/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874777 | 1.00 | CTSL (0.47) | CTSLITGA4ITGB7ALDH1A1L3MBTL1 | |
| SCHEMBL8873387 | 0.87 | ITGA4 (0.52) | CTSLITGA4ITGB7ALDH1A1L3MBTL1 | |
| SCHEMBL8873376 | 0.87 | ITGA4 (0.52) | CTSLITGA4ITGB7ALDH1A1L3MBTL1 | |
| SCHEMBL25308058 | 0.83 | POLB (0.46) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL30507546 | 0.83 | POLB (0.46) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL25308059 | 0.83 | POLB (0.46) | ALDH1A1SMN1; SMN2LMNAGAAMAPT | |
| SCHEMBL8875245 | 0.83 | MMP9 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL29038084 | 0.83 | MMP9 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL8875251 | 0.83 | MMP9 (0.45) | ALDH1A1SMN1; SMN2LMNAMAPTKMT2A | |
| SCHEMBL8873243 | 0.80 | TDP1 (0.41) | ITGA4ITGB7ALDH1A1L3MBTL1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610153-A | ENZYME INHIBITORS; TREATMENT OF VASCULAR PROLIFERATION DISORDERS, STERILITY DYSFUNCTION, DYSMENORRHEA | CIBA-GEIGY CORPORATION (US) | 1997-03-11 | — | — | US | disclosed |