Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CCR5 | P51681 | 2/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875025 | 0.76 | GAA (0.46) | S1PR5S1PR1GAARORCFUCA1 | |
| SCHEMBL8874365 | 0.75 | GAA (0.44) | CYP3A4CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL8874334 | 0.73 | TACR1 (0.40) | S1PR5S1PR1CYP2D6CYP3A4CYP2C19 | |
| SCHEMBL9003052 | 0.70 | TACR1 (0.48) | CYP3A4CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL9003055 | 0.70 | TACR1 (0.48) | CYP3A4CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL9268452 | 0.70 | TACR1 (0.48) | CYP3A4CYP2C19MEN1KMT2AMAPT | |
| SCHEMBL11872365 | 0.69 | TSHR (0.45) | MGLLCYP2D6CYP3A4CYP2C9CYP2C19 | |
| SCHEMBL8875253 | 0.69 | CHRM4 (0.44) | CYP3A4CYP2C19ALDH1A1MEN1KMT2A | |
| SCHEMBL11879597 | 0.69 | LMNA (0.47) | CYP2D6CYP3A4CYP2C9CYP2C19KDM4E | |
| SCHEMBL28934869 | 0.68 | CYP3A4 (0.53) | S1PR5S1PR1CYP2D6CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |