Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 5/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003052 | 1.00 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9003055 | 1.00 | TACR1 (0.48) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729382 | 0.90 | DPP4 (0.46) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729281 | 0.89 | MEN1 (0.43) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729536 | 0.89 | CCR5 (0.42) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL8874365 | 0.87 | GAA (0.44) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9729134 | 0.84 | TACR1 (0.39) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL8875025 | 0.83 | GAA (0.46) | TACR1GAA | |
| SCHEMBL8874334 | 0.80 | TACR1 (0.40) | TACR1MEN1CYP3A4MAPTTSHR | |
| SCHEMBL9730595 | 0.78 | TACR1 (0.58) | TACR1MEN1CYP3A4MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5451601-A | Perhydroisoindole derivatives and pharmaceutical compositions containing them | RHONE-POULENC RORER S.A. (FR) | 1995-09-19 | — | — | US | disclosed |