SCHEMBL887430

SCHEMBL887430

CC(C)(C)OC(=O)C(=[N+]=[N-])C(NC(=O)c1ccccc1)c1ccccc1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
CYP1A2 P05177 4/20 0.42
CYP3A4 P08684 3/20 0.42
TSHR P16473 3/20 0.42
CTSS P25774 1/20 0.42
CTSK P43235 1/20 0.42
LMNA P02545 4/20 0.42
CTRB1 P17538 3/20 0.40
PRSS1 P07477 2/20 0.40
CTSG P08311 2/20 0.40
CMA1 P23946 2/20 0.40
CA1 P00915 1/20 0.40
CA2 P00918 1/20 0.40
HPGD P15428 1/20 0.40
S1PR3 Q99500 2/20 0.39
S1PR4 O95977 1/20 0.39
CYP2C9 P11712 3/20 0.38
CYP2C19 P33261 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
OPRK1 P41145 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL887412 0.82 SMN1; SMN2 (0.49) ALDH1A1CYP1A2CYP3A4TSHRLMNA
SCHEMBL887450 0.77 CTSK (0.53) TSHRCTSSCTSKS1PR3SMN1; SMN2
SCHEMBL887431 0.71 CA12 (0.46) ALDH1A1CA1CA2
SCHEMBL6963259 0.71 LMNA (0.56) ALDH1A1CYP1A2CYP3A4TSHRLMNA
SCHEMBL27453160 0.71 MAPT (0.54) ALDH1A1CTRB1PRSS1CTSGCMA1
SCHEMBL25366914 0.70 TACR3 (0.59) ALDH1A1CYP1A2CYP3A4TSHRLMNA
SCHEMBL28319764 0.70 TDP1 (0.43) ALDH1A1CYP1A2TSHRLMNACTRB1
SCHEMBL9848833 0.70 ALDH1A1 (0.55) ALDH1A1CYP1A2CYP3A4TSHRLMNA
SCHEMBL1649573 0.70 CA1 (0.69) ALDH1A1CYP1A2CYP3A4TSHRLMNA
SCHEMBL18232126 0.70 CA1 (0.69) ALDH1A1CYP1A2CYP3A4TSHRLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7902207-B2 Process for production of amines TAKASAGO INTERNATIONAL CORPORATION (JP) 2011-03-08 US disclosed