Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CASR | P41180 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL28722422 | 0.75 | NAAA (0.37) | ALDH1A1RECQLL3MBTL1CYP1A2CYP2C19 | |
| Hydrochloric Acid SCHEMBL10607352 | 0.75 | NAAA (0.37) | ALDH1A1RECQLL3MBTL1CYP1A2CYP2C19 | |
| SCHEMBL6376438 | 0.73 | LPAR3 (0.44) | — | |
| Hydrochloric Acid SCHEMBL31556345 | 0.73 | KCNN4 (0.41) | TSHRALDH1A1TDP1L3MBTL1KMT2A | |
| SCHEMBL12681583 | 0.72 | LTA4H (0.38) | TSHRALDH1A1TDP1L3MBTL1LTA4H | |
| O-Xylene SCHEMBL828368 | 0.72 | TSHR (0.48) | TSHRALDH1A1HPGDRECQLTDP1 | |
| SCHEMBL11895182 | 0.68 | ALDH1A1 (0.49) | TSHRALDH1A1HPGDRECQLTDP1 | |
| SCHEMBL27495356 | 0.68 | LTA4H (0.39) | TSHRALDH1A1LTA4HKMT2ACYP1A2 | |
| SCHEMBL11879214 | 0.68 | MAPT (0.37) | ALDH1A1HPGDL3MBTL1KMT2ACYP2C9 | |
| SCHEMBL23183020 | 0.68 | PTPRC (0.42) | ALDH1A1L3MBTL1POLBADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5624950-A | USEFUL IN TREATMENT OF ANALGESIA, INFLAMMATION, ASTHMA, ALLERGIES, CENTRAL NERVOUS SYSTEM DISORDERS, CARDIOVASCULAR DISORDERS, IMMUNE SYSTEM DISORDERS, ANTISPASMODIC AGENTS, ANTIEMETIC AGENTS | RHONE-POULENC RORER S.A. (FR) | 1997-04-29 | — | — | US | disclosed |