Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.48 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | LTA4H | P09960 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| O-Xylene SCHEMBL29084625 | 0.93 | LTA4H (0.47) | TSHRACHEALDH1A1LTA4HHPGD | |
| Butoxyethanol SCHEMBL6416346 | 0.90 | TSHR (0.65) | TSHRALDH1A1LTA4HHPGDCYP1A2 | |
| Orthocresol SCHEMBL10343638 | 0.86 | TSHR (0.43) | TSHRALDH1A1LTA4HHPGDCYP1A2 | |
| O-Xylene SCHEMBL27742544 | 0.85 | ACHE (0.53) | TSHRACHEALDH1A1LTA4HHPGD | |
| Toluene SCHEMBL349785 | 0.84 | TSHR (0.50) | TSHRACHEALDH1A1LTA4HHPGD | |
| SCHEMBL1710089 | 0.82 | CYP2C19 (0.53) | TSHRALDH1A1HPGDCYP1A2CYP2C9 | |
| Iodobenzene SCHEMBL27895666 | 0.82 | TSHR (0.49) | TSHRALDH1A1LTA4HHPGDCYP1A2 | |
| O-Xylene SCHEMBL10970480 | 0.82 | TSHR (0.62) | TSHRACHEALDH1A1LTA4HCYP1A2 | |
| O-Xylene SCHEMBL7939277 | 0.82 | TSHR (0.62) | TSHRACHEALDH1A1LTA4HCYP1A2 | |
| O-Xylene SCHEMBL10976233 | 0.82 | TSHR (0.62) | TSHRACHEALDH1A1LTA4HCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107036860-A | Tissue treatment reagent | 美国樱花检验仪器株式会社 | 2017-08-11 | — | — | CN | disclosed |
| CN-105017450-B | Polyvinyl ether synthesis method | 湖北荆洪生物科技股份有限公司 | 2017-02-01 | — | — | CN | disclosed |
| CN-101434546-B | Synthesis method of 2, 6-dinitro-3, 4-xylyl alkyl ether | UNIV ZHEJIANG TECHNOLOGY | 2012-05-23 | — | — | CN | disclosed |
| US-8143463-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2012-03-27 | — | — | US | disclosed |
| CN-101309913-B | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LTD | 2011-05-25 | — | — | CN | disclosed |
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2011-04-21 | — | — | US | disclosed |
| US-7910730-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-22 | — | — | US | disclosed |
| US-7901527-B2 | Microchip manufacturing method | KONICA MINOLTA OPTO, INC. (JP) | 2011-03-08 | — | — | US | disclosed |
| US-7902357-B2 | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2011-03-08 | — | — | US | disclosed |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | ARTUS SURROCA JUAN JOSE | 2010-09-02 | — | — | US | disclosed |
| EP-2116853-A1 | MICROCHIP MANUFACTURING METHOD | Konica Minolta Opto, Inc. (JP) | 2009-11-11 | — | — | EP | disclosed |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2009-05-28 | — | — | US | disclosed |
| CN-101434546-A | Method for synthesizing 2,6- binitro-3,4-xylyl alkyl ether | UNIV ZHEJIANG TECHNOLOGY (CN) | 2009-05-20 | — | — | CN | disclosed |
| EP-1948626-B1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LTD (GB) | 2009-03-04 | — | — | EP | disclosed |
| CN-101309913-A | Process for the preparation of delmopinol and derivatives thereof | SINCLAIR PHARMACEUTICALS LTD (GB) | 2008-11-19 | — | — | CN | disclosed |
| EP-1948626-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | Sinclair Pharmaceuticals Limited (GB) | 2008-07-30 | — | — | EP | disclosed |
| WO-2007057681-A1 | PROCESS FOR THE PREPARATION OF DELMOPINOL AND DERIVATIVES THEREOF | SINCLAIR PHARMACEUTICALS LIMITED (GB) | 2007-05-24 | — | — | WO | disclosed |
| CN-1052490-C | Method for increasing alpha to beta ratio in aspartame coupling reaction | NUTRASWEET CO (US) | 2000-05-17 | — | — | CN | disclosed |
| CN-1055539-A | The method of α and beta ratio in raising L-aspartyl-L-phenyl methyl lactamine coupled reaction | NUTRASWEET CO (US) | 1991-10-23 | — | — | CN | disclosed |
| US-4758620-A | Blend of solvent and arylsiloxane interlayer dielectric materials | AKZO AMERICA INC. (US) | 1988-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110092751-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | TSHR 950/4885ACHE 2011/4885ALDH1A1 2327/4885 |
| US-20100222579-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | TSHR 950/4885ACHE 2011/4885ALDH1A1 2327/4885 |
| US-20090137798-A1 | Process for the Preparation of Delmopinol and Derivatives Thereof | MDN1, MCOLN3, EML4 | TSHR 943/4885ACHE 1995/4885ALDH1A1 2353/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.