Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 11/20 | 0.42 |
| ▸ | SMPD1 | P17405 | 4/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876183 | 0.93 | SMN1; SMN2 (0.42) | MEN1KMT2APPARGSMPD1 | |
| SCHEMBL8875618 | 0.93 | SMN1; SMN2 (0.42) | MEN1KMT2APPARGSMPD1 | |
| SCHEMBL8874498 | 0.89 | SMN1; SMN2 (0.44) | MEN1KMT2ASMPD1 | |
| SCHEMBL8915786 | 0.88 | EGLN1 (0.42) | SMPD1 | |
| SCHEMBL8915832 | 0.88 | EGLN1 (0.42) | SMPD1 | |
| SCHEMBL8098997 | 0.87 | PPARG (0.45) | MEN1KMT2APPARGSMPD1 | |
| SCHEMBL8883945 | 0.84 | MEN1 (0.51) | MEN1KMT2ASMPD1 | |
| SCHEMBL8882066 | 0.84 | MEN1 (0.51) | MEN1KMT2ASMPD1 | |
| SCHEMBL8915506 | 0.84 | EGLN1 (0.43) | SMPD1 | |
| SCHEMBL8882411 | 0.84 | MEN1 (0.51) | MEN1KMT2ASMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5620996-A | Sulfonamidocarbonyl pyridine-2-carboxesteramides and their pyridine-N-oxide compounds and their use as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-04-15 | — | — | US | disclosed |