Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 15/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.41 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | VEGFA | P15692 | 1/20 | 0.37 |
| ▸ | FLT1 | P17948 | 1/20 | 0.37 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8915832 | 0.96 | EGLN1 (0.42) | EGLN1GABRA5SMPD1 | |
| SCHEMBL8915786 | 0.96 | EGLN1 (0.42) | EGLN1GABRA5SMPD1 | |
| SCHEMBL8874498 | 0.89 | SMN1; SMN2 (0.44) | EGLN1GABRA5SMPD1VEGFAFLT1 | |
| SCHEMBL8916805 | 0.86 | GABRA5 (0.39) | EGLN1GABRA5SMPD1VEGFAFLT1 | |
| SCHEMBL8767779 | 0.86 | GABRA5 (0.39) | GABRA5SMPD1 | |
| SCHEMBL8875618 | 0.85 | SMN1; SMN2 (0.42) | GABRA5SMPD1 | |
| SCHEMBL8876183 | 0.85 | SMN1; SMN2 (0.42) | GABRA5SMPD1 | |
| SCHEMBL8874924 | 0.85 | SMPD1 (0.44) | GABRA5SMPD1 | |
| SCHEMBL8875849 | 0.85 | SMPD1 (0.44) | GABRA5SMPD1 | |
| SCHEMBL8874879 | 0.84 | MEN1 (0.46) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5610172-A | Sulfonamidocarbonylpyridine-2-carboxamides and pyridine-n-oxides which are useful as pharmaceuticals | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-03-11 | — | — | US | disclosed |