Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A11 | P48066 | 7/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.40 |
| ▸ | SLC6A12 | P48065 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SLC6A13 | Q9NSD5 | 1/20 | 0.36 |
| ▸ | KIF11 | P52732 | 3/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14959857 | 0.85 | SLC6A11 (0.39) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL887499 | 0.84 | SLC6A11 (0.37) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL5576902 | 0.82 | SLC6A11 (0.38) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL2631346 | 0.82 | SLC6A11 (0.43) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL30434706 | 0.81 | SLC6A11 (0.39) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL13778500 | 0.78 | CYP3A4 (0.36) | CYP3A4 | |
| SCHEMBL30435129 | 0.78 | SLC6A11 (0.38) | SLC6A11SLC6A1SLC6A12MEN1TP53 | |
| SCHEMBL21873599 | 0.78 | KMT2A (0.39) | SLC6A11SLC6A1MEN1KMT2AKIF11 | |
| SCHEMBL21873564 | 0.78 | KMT2A (0.39) | SLC6A11SLC6A1MEN1KMT2AKIF11 | |
| SCHEMBL21873562 | 0.78 | KMT2A (0.39) | SLC6A11SLC6A1MEN1KMT2AKIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9999866-B2 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2018-06-19 | — | — | US | disclosed |
| US-20170145499-A1 | METHODS FOR INDEXING SAMPLES AND SEQUENCING MULTIPLE POLYNUCLEOTIDE TEMPLATES | ILLUMINA CAMBRIDGE LIMITED (US) | 2017-05-25 | — | — | US | disclosed |
| US-20170021325-A1 | Preparation of Templates for Nucleic Acid Sequencing | SOLEXA LIMITED (GB) | 2017-01-26 | — | — | US | disclosed |
| US-9512478-B2 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-12-06 | — | — | US | disclosed |
| US-9498763-B2 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-11-22 | — | — | US | disclosed |
| US-20160090623-A1 | METHOD FOR PAIRWISE SEQUENCING OF TARGET POLYNUCLEOTIDES | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-03-31 | — | — | US | disclosed |
| US-9267173-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2016-02-23 | — | — | US | disclosed |
| US-20150343410-A1 | Preparation of Templates for Nucleic Acid Sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-12-03 | — | — | US | disclosed |
| US-9085802-B2 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2015-07-21 | — | — | US | disclosed |
| US-20140349891-A1 | Preparation of Templates for Nucleic Acid Sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2014-11-27 | — | — | US | disclosed |
| US-8105784-B2 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-01-31 | — | — | US | disclosed |
| US-20120015823-A1 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LIMITED (GB) | 2012-01-19 | — | — | US | disclosed |
| US-8053192-B2 | Methods for indexing samples and sequencing multiple polynucleotide templates | ILLUMINA CAMBRIDGE LTD. (GB) | 2011-11-08 | — | — | US | disclosed |
| US-20110223601-A1 | Method for pairwise sequencing of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2011-09-15 | — | — | US | disclosed |
| US-7960120-B2 | Method for pair-wise sequencing a plurality of double stranded target polynucleotides | ILLUMINA CAMBRIDGE LTD. (GB) | 2011-06-14 | — | — | US | disclosed |
| US-20110014657-A1 | Method for sequencing a polynucleotide template | ILLUMINA CAMBRIDGE LTD. | 2011-01-20 | — | — | US | disclosed |
| US-7754429-B2 | Method for pair-wise sequencing a plurity of target polynucleotides | ILLUMINA CAMBRIDGE LIMITED (GB) | 2010-07-13 | — | — | US | disclosed |
| US-20090233802-A1 | Methods for indexing samples and sequencing multiple polynucleotide templates | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2009-09-17 | — | — | US | disclosed |
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | ILLUMINA CAMBRIDGE LIMITED (GB) | 2009-05-07 | — | — | US | disclosed |
| US-20090088327-A1 | Method for sequencing a polynucleotide template | SOLEXA LIMITED (GB) | 2009-04-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090118128-A1 | Preparation of templates for nucleic acid sequencing | RNGTT, POLRMT, POLM | SLC6A11 4807/4885SLC6A1 4778/4885SLC6A12 3773/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.