Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 4/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535652 | 0.83 | ALDH1A1 (0.41) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL11408828 | 0.76 | NTRK1 (0.52) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8875255 | 0.76 | MAOB (0.51) | MEN1KMT2AL3MBTL1CYP1A2 | |
| SCHEMBL30660067 | 0.75 | MEN1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL8011548 | 0.75 | MEN1 (0.50) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL4813089 | 0.73 | MAPT (0.45) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL9388552 | 0.71 | MAOB (0.44) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL7402520 | 0.71 | CA12 (0.53) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL3441080 | 0.70 | CDC25A (0.51) | MEN1KMT2AL3MBTL1ALDH1A1MAPT | |
| SCHEMBL29612422 | 0.68 | GAA (0.53) | MEN1KMT2AL3MBTL1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292606-A4 | POSITIVELY-CHARGED PEPTIDE NUCLEIC ACID ANALOGS WITH IMPROVED PROPERTIES | YISSUM RES DEV CO (IL) | 2004-03-24 | — | — | EP | disclosed |
| EP-1292606-A2 | POSITIVELY-CHARGED PEPTIDE NUCLEIC ACID ANALOGS WITH IMPROVED PROPERTIES | Yissum Research Development Company of the Hebrew University of Jerusalem (IL) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098522-A2 | POSITIVELY-CHARGED PEPTIDE NUCLEIC ACID ANALOGS WITH IMPROVED PROPERTIES | YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM (IL) | 2001-12-27 | — | — | WO | disclosed |