Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.54 |
| ▸ | P4HTM | Q9NXG6 | 4/20 | 0.52 |
| ▸ | EGFR | P00533 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.44 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.44 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8767487 | 0.92 | PTGS2 (0.55) | PTGS2PTGS1P4HTMEGFRGAA | |
| Hydrochloric Acid SCHEMBL9231980 | 0.91 | PTGS2 (0.54) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8766943 | 0.85 | PTGS2 (0.48) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8767482 | 0.82 | PTGS2 (0.58) | PTGS2PTGS1P4HTMEGFRGAA | |
| Hydrochloric Acid SCHEMBL8915942 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8875655 | 0.81 | PTGS2 (0.56) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL8104048 | 0.81 | PTGS2 (0.44) | PTGS2PTGS1P4HTMEGFRGAA | |
| SCHEMBL7870518 | 0.79 | P4HTM (0.64) | PTGS2PTGS1P4HTMEGFRMCL1 | |
| SCHEMBL8090536 | 0.77 | PTGS2 (0.47) | PTGS2P4HTMPKM | |
| SCHEMBL8099332 | 0.77 | MEN1 (0.41) | PTGS2PTGS1P4HTMEGFRMCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673931-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |
| EP-0673932-A1 | Sulfonamidocarbonyl-pyridine-2-carboxamides as well as their pyridine-N-oxides, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-09-27 | — | — | EP | disclosed |