Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RECQL | P46063 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | CTSV | O60911 | 3/20 | 0.52 |
| ▸ | CTSL | P07711 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | AR | P10275 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29502844 | 0.94 | POLB (0.58) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL5421861 | 0.94 | POLB (0.58) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL8947705 | 0.92 | KMT2A (0.49) | RAB9ANPC1RECQLPOLBKMT2A | |
| SCHEMBL12530118 | 0.89 | ALDH1A1 (0.54) | RAB9ANPC1RECQLPOLBKMT2A | |
| SCHEMBL3997761 | 0.87 | MEN1 (0.67) | RAB9ANPC1POLBKMT2AMEN1 | |
| SCHEMBL8947775 | 0.87 | CTSV (0.46) | RAB9ANPC1RECQLPOLBKMT2A | |
| SCHEMBL7402862 | 0.87 | POLB (0.52) | RAB9ANPC1RECQLPOLBKMT2A | |
| SCHEMBL27481728 | 0.86 | PKM (0.57) | RAB9ANPC1RECQLPOLBKMT2A | |
| SCHEMBL30832846 | 0.85 | MEN1 (0.57) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL1663438 | 0.85 | MEN1 (0.57) | RAB9ANPC1KMT2AMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602258-A | Azide-containing chelators whose affinity for calcium ion is decreased by illumination | THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) | 1997-02-11 | — | — | US | disclosed |
| US-5552555-A | Azide-containing chelators whose affinity for calcium ion is decreased by illumination | THE REGENTS OF UNIVERSITY OF CALIFORNIA (US) | 1996-09-03 | — | — | US | disclosed |
| US-5501980-A | Benzazolylcoumarin-based ion indicators | MOLECULAR PROBES, INC. (US) | 1996-03-26 | — | — | US | disclosed |