Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSV | O60911 | 3/20 | 0.46 |
| ▸ | CTSL | P07711 | 3/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RECQL | P46063 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875982 | 0.87 | RAB9A (0.55) | CTSVCTSLHTR1AADRA1DADRA1A | |
| SCHEMBL1041077 | 0.83 | PTGES (0.48) | CTSVCTSLPTGESHTR1AADRA1D | |
| SCHEMBL5421861 | 0.82 | POLB (0.58) | CTSVCTSLPTGESKMT2AMEN1 | |
| SCHEMBL29502844 | 0.82 | POLB (0.58) | CTSVCTSLPTGESKMT2AMEN1 | |
| SCHEMBL29503061 | 0.81 | PTGES (0.61) | CTSVCTSLPTGESKMT2AMEN1 | |
| SCHEMBL2022545 | 0.81 | PTGES (0.61) | CTSVCTSLPTGESKMT2AMEN1 | |
| SCHEMBL8947705 | 0.80 | KMT2A (0.49) | CTSVCTSLHTR1AADRA1DADRA1A | |
| SCHEMBL12530118 | 0.80 | ALDH1A1 (0.54) | KMT2AMEN1MAPTPOLBRAB9A | |
| SCHEMBL29463874 | 0.78 | PTGES (0.61) | CTSVCTSLPTGESKMT2AMEN1 | |
| SCHEMBL519418 | 0.78 | PTGES (0.61) | CTSVCTSLPTGESKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516911-A | Fluorescent intracellular calcium indicators | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 1996-05-14 | — | — | US | disclosed |