Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 5/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL456636 | 0.81 | PDK1 (0.41) | KMT2AMEN1SMN1; SMN2ALDH1A1PDK1 | |
| SCHEMBL3604296 | 0.80 | ALDH1A1 (0.39) | CYP1A2KMT2AMEN1ALDH1A1POLB | |
| SCHEMBL16950649 | 0.78 | MAPT (0.36) | ALDH1A1PDK1CYP3A4LMNAMAPT | |
| SCHEMBL28355811 | 0.76 | ALOX15 (0.40) | CYP1A2KMT2AMEN1ALDH1A1PDK1 | |
| SCHEMBL31046181 | 0.76 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6205054 | 0.76 | ALDH1A1 (0.36) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL11152901 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1ALDH1A1POLBCYP3A4 | |
| SCHEMBL359218 | 0.76 | KMT2A (0.59) | KMT2AMEN1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL11151232 | 0.75 | ALDH1A1 (0.39) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL27420001 | 0.75 | ALDH1A1 (0.40) | CYP1A2SMN1; SMN2ALDH1A1L3MBTL1CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5693634-A | FOR SYSTEMIC AND TOPICAL TREATMENT OF HUMANS AND ANIMALS; VETERINARY MEDICINE | GLAXO WELLCOME S.P.A. (IT) | 1997-12-02 | — | — | US | disclosed |