Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
| ▸ | PTGES | O14684 | 7/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PDE2A | O00408 | 6/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.32 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 2/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875393 | 0.99 | HSD11B1 (0.36) | HSD11B1PTGESKDM4ENPSR1PDE2A | |
| SCHEMBL8876099 | 0.86 | HSD11B1 (0.38) | HSD11B1PDE2APDE10ANR1H2NR1H3 | |
| SCHEMBL9251182 | 0.82 | MAPT (0.38) | PTGESKDM4ENPSR1PDE2APDE10A | |
| SCHEMBL8303382 | 0.75 | HSD17B2 (0.34) | PTGESKDM4ENPSR1PDE2APDE10A | |
| SCHEMBL9830092 | 0.74 | HSD11B1 (0.51) | HSD11B1PTGES | |
| SCHEMBL5727268 | 0.74 | HSD11B1 (0.38) | HSD11B1PTGESKDM4ENPSR1PDE2A | |
| SCHEMBL8304433 | 0.74 | HSD11B1 (0.51) | HSD11B1PTGESPDE2APDE10ANR1H2 | |
| SCHEMBL5727760 | 0.73 | KDM4E (0.42) | HSD11B1PTGESKDM4ENPSR1NR1H2 | |
| SCHEMBL5726302 | 0.73 | KDM4E (0.42) | HSD11B1PTGESKDM4ENPSR1PDE2A | |
| SCHEMBL5727040 | 0.73 | HSD11B1 (0.37) | HSD11B1PTGESKDM4ENPSR1PDE2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5700824-A | Triazole derivatives, insecticide, acaricide and methods thereof | KUMIAI CHEMICAL INDUSTRIAL CO. LTD. (JP) | 1997-12-23 | — | — | US | disclosed |
| US-5616594-A | Triazole derivatives, insecticide, acaricide and methods thereof | IHARA CHEMICAL INDUSTRY CO. LTD. (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0648752-A1 | TRIAZOLE DERIVATIVE, INSECTICIDAL/ACARICIDAL AGENT, AND PROCESS FOR PRODUCING THE SAME | KUMIAI CHEMICAL INDUSTRY CO., LTD. (JP) | 1995-04-19 | — | — | EP | disclosed |