Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.38 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.38 |
| ▸ | PTGES | O14684 | 5/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | MAT2A | P31153 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8875393 | 0.83 | HSD11B1 (0.36) | NR1H2NR1H3PTGESPTGS1KDM4E | |
| SCHEMBL8876286 | 0.82 | HSD11B1 (0.35) | NR1H2NR1H3PTGESPTGS1KDM4E | |
| SCHEMBL4611925 | 0.82 | PTGES (0.46) | MAPTNR1H2NR1H3PTGESPTGS1 | |
| SCHEMBL5727209 | 0.80 | MAPT (0.42) | MAPTNR1H2NR1H3PTGESPTGS1 | |
| SCHEMBL8303382 | 0.79 | HSD17B2 (0.34) | NR1H2NR1H3PTGESNPC1RAB9A | |
| SCHEMBL8304815 | 0.78 | NR1H2 (0.43) | NR1H2NR1H3PTGESPTGS1NPC1 | |
| SCHEMBL5727286 | 0.77 | PTGES (0.42) | MAPTPTGESPTGS1KDM4ENPSR1 | |
| SCHEMBL8942725 | 0.77 | NR1H2 (0.49) | MAPTNR1H2NR1H3PTGESNPC1 | |
| SCHEMBL8303453 | 0.77 | HSD17B2 (0.44) | MAPTNR1H2NR1H3PTGESNPC1 | |
| SCHEMBL5727182 | 0.75 | PTGES (0.41) | MAPTPTGESPTGS1KDM4ENPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-7076577-A | — | — | None | — | — | JP | disclosed |
| JP-H0776577-A | DIPHENYLTRIAZOLE DERIVATIVE AND INSECTICIDE AND ACARICIDE | KUMIAI CHEM IND CO LTD | 1995-03-20 | — | — | JP | disclosed |