Sugi Predict

Sugi Predict / Compounds / SCHEMBL8876591

SCHEMBL8876591

SCHEMBL8876591

CN(C)c1ccccc1P(C12CC3CC(CC(C3)C1)C2)C12CC3CC(CC(C3)C1)C2

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ GRIN2D O15399 1/20 0.35
▸ GRIN3B O60391 1/20 0.35
▸ GRIN1 Q05586 1/20 0.35
▸ GRIN2A Q12879 1/20 0.35
▸ GRIN2B Q13224 1/20 0.35
▸ GRIN2C Q14957 1/20 0.35
▸ GRIN3A Q8TCU5 1/20 0.35
▸ EPHX2 P34913 3/20 0.33
▸ MEN1 O00255 1/20 0.33
▸ RAB9A P51151 1/20 0.33
▸ KMT2A Q03164 1/20 0.33
▸ HSD11B1 P28845 3/20 0.32
▸ FAAH O00519 2/20 0.32
▸ P2RX7 Q99572 1/20 0.31
▸ OPRK1 P41145 1/20 0.31
▸ ALDH1A1 P00352 1/20 0.31
▸ TP53 P04637 1/20 0.31
▸ GAA P10253 1/20 0.31
▸ MAPT P10636 1/20 0.31
▸ TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30759700 1.00 GRIN2D (0.35) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL19469295 0.95 GRIN2D (0.32) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL6109500 0.82 FAAH (0.39) EPHX2FAAHP2RX7ALDH1A1MAPT
SCHEMBL8892227 0.78 — —
SCHEMBL15275551 0.77 SIGMAR1 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL30402889 0.77 SIGMAR1 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL4433788 0.71 MEN1 (0.43) EPHX2MEN1KMT2AHSD11B1FAAH
SCHEMBL15658232 0.71 MEN1 (0.39) GRIN2DGRIN3BGRIN1GRIN2AGRIN2B
SCHEMBL31568154 0.70 FAAH (0.34) EPHX2MEN1KMT2AFAAHCNR2
SCHEMBL15358693 0.70 FAAH (0.34) EPHX2MEN1KMT2AFAAHCNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 81 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same YALE UNIVERSITY (US) 2025-02-25 — — US claimed
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME UNIV YALE (US) 2025-01-02 — — US claimed
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2024-08-27 — — US claimed
US-20230203077-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME NATIONAL SCIENCE FOUNDATION 2023-06-29 — — US claimed
CN-113262816-B Catalytic system and method for synthesizing benzo [1,2-b:4,5-b' ] dibenzofuran by using same 中钢集团南京新材料研究院有限公司 2023-06-20 — — CN claimed
CN-116082157-A Method for preparing organic carboxylic ester by olefine unsaturated compound alkoxycarbonyl reaction 上海梓龄化工技术有限公司 2023-05-09 — — CN claimed
CN-114105922-B Synthesis method of hydroxypropyl tetrahydropyran triol 北京富盛嘉华医药科技有限公司 2023-05-02 — — CN claimed
US-11603381-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same YALE UNIVERSITY (US) 2023-03-14 — — US claimed
CN-114105922-A Synthesis method of hydroxypropyl tetrahydropyrane triol 北京富盛嘉华医药科技有限公司 2022-03-01 — — CN claimed
CN-113262816-A Catalytic system and method for synthesizing benzo [1,2-b:4,5-b ] dibenzofuran by using same 中钢集团南京新材料研究院有限公司 2021-08-17 — — CN claimed
WO-2019016115-A1 PROCESS FOR THE PREPARATION OF SUBSTITUTED ARYL KETONES BASF Agro B.V. (NL) 2019-01-24 — — WO claimed
US-20260103443-A1 CHEMICAL COMPOUND LMS CO LTD (KR) 2026-04-16 — — US disclosed
EP-3609891-B1 SUBSTITUTED HETEROCYCLE FUSED GAMMA-CARBOLINES SYNTHESIS INTRA CELLULAR THERAPIES INC (US) 2026-02-11 — — EP disclosed
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES BHATTACHARYA SHRABANTI (US) 2025-12-04 — — US disclosed
WO-2025235874-A1 HETEROCYCLICS AS EGFR INHIBITORS SCHRÖDINGER, INC. (US) 2025-11-13 — — WO disclosed
WO-2014128067-A1 BICYCLO 2,3-BENZODIAZEPINES AND SPIROCYCLICALLY SUBSTITUTED 2,3-BENZODIAZEPINES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2014-08-28 — — WO disclosed
US-20130253185-A1 NOVEL CATALYSTS DALHOUSIE UNIVERSITY (CA) 2013-09-26 — — US disclosed
US-20130253185-A1 NOVEL CATALYSTS DALHOUSIE UNIVERSITY (CA) 2013-09-26 — — US disclosed
US-20130253185-A1 NOVEL CATALYSTS DALHOUSIE UNIVERSITY (CA) 2013-09-26 — — US disclosed
WO-2012068335-A2 NOVEL CATALYSTS DALHOUSIE UNIVERSITY (CA) 2012-05-24 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368598-A1 CATALYTIC CARBOXYCARBONYLATION OF ALKENES TO FORM ANHYDRIDES CA4, CA12, CA14 GRIN2D 3701/4885GRIN3B 3320/4885GRIN1 2864/4885
US-20250002519-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 GRIN2D 4419/4885GRIN3B 4260/4885GRIN1 4263/4885
US-11603381-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 GRIN2D 4519/4885GRIN3B 4276/4885GRIN1 4489/4885
US-20260103443-A1 CHEMICAL COMPOUND RAD51, CBR1, NOS1 GRIN2D 1110/4885GRIN3B 1878/4885GRIN1 636/4885
US-20230203077-A1 NOVEL PRECATALYST SCAFFOLDS FOR CROSS-COUPLING REACTIONS, AND METHODS OF MAKING AND USING SAME TIMCC, YAP1, TET2 GRIN2D 4419/4885GRIN3B 4260/4885GRIN1 4263/4885
US-12233402-B2 Cross-coupling reaction catalysts, and methods of making and using same TET2, TIMCC, MDM4 GRIN2D 4537/4885GRIN3B 4132/4885GRIN1 3983/4885
US-12071445-B2 Precatalyst scaffolds for cross-coupling reactions, and methods of making and using same TIMCC, YAP1, TET2 GRIN2D 4519/4885GRIN3B 4276/4885GRIN1 4489/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.