Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 2/20 | 0.40 |
| ▸ | KMO | O15229 | 6/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ESPL1 | Q14674 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CD74 | P04233 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30690120 | 0.76 | LMNA (0.44) | KDM4ELMNAMAPTHTTNPSR1 | |
| SCHEMBL19415673 | 0.71 | KMO (0.71) | IDO1KMOMAPTKMT2A | |
| SCHEMBL8292029 | 0.69 | GRIK1 (0.50) | — | |
| SCHEMBL15323840 | 0.67 | MAPT (0.76) | KDM4ELMNAMAPTHTTNPSR1 | |
| SCHEMBL15324212 | 0.67 | MAPT (0.59) | KDM4ELMNAMAPTHTTNPSR1 | |
| SCHEMBL1027908 | 0.67 | HTT (0.50) | KDM4ELMNAMAPTHTTNPSR1 | |
| SCHEMBL31451497 | 0.67 | KMT2A (0.61) | IDO1KMT2AALDH1A1CD74MIF | |
| SCHEMBL31717113 | 0.67 | GLS (0.44) | KMOKDM4ELMNAMAPTHTT | |
| SCHEMBL782891 | 0.66 | SIGMAR1 (0.57) | IDO1KMONPSR1KMT2AALDH1A1 | |
| SCHEMBL10913762 | 0.65 | MAPT (0.47) | KDM4ELMNAMAPTHTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5631209-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1997-05-20 | — | — | US | disclosed |
| US-5502027-A | ALGICIDES | ROHM AND HAAS COMPANY (US) | 1996-03-26 | — | — | US | disclosed |
| US-5393735-A | N-(halo-oxy-)phenyl substituted cyclic imides | ROHM AND HAAS COMPANY (US) | 1995-02-28 | — | — | US | disclosed |
| US-5238908-A | HERBICIDAL GLUTARAMIC ACIDS AND DERIVATIVES | ROHM AND HAAS COMPANY (US) | 1993-08-24 | — | — | US | disclosed |
| EP-0415641-A1 | Substituted glutaramic acids and derivatives | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |
| EP-0415642-A1 | Glutarimides | ROHM AND HAAS COMPANY (US) | 1991-03-06 | — | — | EP | disclosed |