Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | PDE4A | P27815 | 1/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8874964 | 0.87 | MAPT (0.58) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL8875692 | 0.86 | LMNA (0.47) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL10710173 | 0.84 | MAPT (0.68) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL8876075 | 0.81 | ALDH1A1 (0.64) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL10839762 | 0.78 | LMNA (0.53) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL10840925 | 0.77 | ALOX5 (0.56) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL10842338 | 0.77 | LMNA (0.52) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL27347476 | 0.77 | MAPT (0.57) | MAPTALDH1A1LMNAKDM4EHTR1A | |
| SCHEMBL20346587 | 0.77 | ABCG2 (0.47) | MAPTALDH1A1KDM4ECYP1A2GLA | |
| SCHEMBL10842711 | 0.76 | ALDH1A1 (0.57) | MAPTALDH1A1LMNAKDM4EHTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5605896-A | Bicyclic heterocyclic derivatives having α1 adrenergic and 5HT1A activities | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1997-02-25 | — | — | US | disclosed |