Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 13/20 | 0.60 |
| ▸ | MAOB | P27338 | 6/20 | 0.57 |
| ▸ | PTPN2 | P17706 | 11/20 | 0.54 |
| ▸ | CDC25B | P30305 | 11/20 | 0.54 |
| ▸ | PARP15 | Q460N3 | 2/20 | 0.50 |
| ▸ | PARP10 | Q53GL7 | 2/20 | 0.50 |
| ▸ | PTPN6 | P29350 | 7/20 | 0.49 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29118407 | 0.86 | MAOB (0.71) | PTPN1MAOBPARP15PARP10PARP14 | |
| SCHEMBL8876594 | 0.85 | PTPN1 (0.60) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL8877320 | 0.85 | PTPN1 (0.64) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL7239415 | 0.80 | MAOB (0.58) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL8877502 | 0.80 | PARP10 (0.58) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL5382714 | 0.80 | ALOX5 (0.71) | MAOB | |
| SCHEMBL12443168 | 0.79 | PTPN1 (0.53) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL978095 | 0.76 | PTPN1 (0.51) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL4244280 | 0.75 | PTPN1 (0.56) | PTPN1MAOBPTPN2CDC25BPARP15 | |
| SCHEMBL5968422 | 0.75 | PTPN1 (0.50) | PTPN1MAOBPTPN2CDC25BPARP15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |
| EP-1457490-A1 | 5-membered N-heterocyclic compounds with hypoglycemic and hypolipidemic activity | Takeda Chemical Industries, Ltd. (JP) | 2004-09-15 | — | — | EP | disclosed |
| EP-1228067-B1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2004-07-14 | — | — | EP | disclosed |
| EP-1228067-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGYLCEMIC AND HYPOLIPIDEMIC ACTIVITY | Takeda Chemical Industries, Ltd. (JP) | 2002-08-07 | — | — | EP | disclosed |
| WO-2001038325-A1 | 5-MEMBERED N-HETEROCYCLIC COMPOUNDS WITH HYPOGLYCEMIC AND HYPOLIPIDEMIC ACTIVITY | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2001-05-31 | — | — | WO | disclosed |