Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CNR2 | P34972 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | NCF1 | P14598 | 1/20 | 0.32 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | GRM5 | P41594 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8876593 | 0.88 | KEAP1 (0.39) | CNR2LMNAHTTHSD11B1SMN1; SMN2 | |
| SCHEMBL8877389 | 0.86 | KEAP1 (0.41) | SIGMAR1CNR2LMNAHTTHSD11B1 | |
| SCHEMBL8875969 | 0.86 | KEAP1 (0.41) | SIGMAR1CNR2LMNAHTTHSD11B1 | |
| SCHEMBL8875976 | 0.85 | ALDH1A1 (0.38) | SIGMAR1CNR2LMNAHTTHSD11B1 | |
| SCHEMBL8877384 | 0.84 | SIGMAR1 (0.47) | SIGMAR1CNR2LMNAHTTNCF1 | |
| SCHEMBL8891248 | 0.82 | KEAP1 (0.37) | SIGMAR1CNR2LMNAHTTHSD11B1 | |
| SCHEMBL8881580 | 0.79 | SIGMAR1 (0.47) | SIGMAR1LMNANCF1HPGDALDH1A1 | |
| SCHEMBL8883193 | 0.79 | MAPK1 (0.31) | CNR2HSD11B1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL8877351 | 0.79 | EPHX2 (0.32) | CNR2HSD11B1SMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL8881515 | 0.78 | GAA (0.33) | CNR2LMNAHTTGAAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |
| US-20130253185-A1 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2013-09-26 | — | — | US | disclosed |
| WO-2012068335-A2 | NOVEL CATALYSTS | DALHOUSIE UNIVERSITY (CA) | 2012-05-24 | — | — | WO | disclosed |