Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 3/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CTH | P32929 | 1/20 | 0.39 |
| ▸ | CBS | P35520 | 1/20 | 0.39 |
| ▸ | THPO | P40225 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9813656 | 0.74 | GRIK1 (0.55) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6341738 | 0.72 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6682947 | 0.72 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL13917775 | 0.72 | GRIK1 (0.46) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165762 | 0.70 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL8399846 | 0.69 | GRIK1 (1.00) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL30727799 | 0.68 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6555623 | 0.67 | GRIK1 (0.43) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL14598192 | 0.67 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6551852 | 0.67 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5602196-A | OXIDATION AND HEAT RESISTANCE; PHOTOSTABILITY | CIBA-GEIGY CORPORATION (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0716076-A2 | Bisphenolester derivatives | CIBA-GEIGY AG (CH) | 1996-06-12 | — | — | EP | disclosed |