Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3E | A5X5Y0 | 10/20 | 0.61 |
| ▸ | HTR3B | O95264 | 10/20 | 0.61 |
| ▸ | HTR3A | P46098 | 10/20 | 0.61 |
| ▸ | HTR3D | Q70Z44 | 10/20 | 0.61 |
| ▸ | HTR3C | Q8WXA8 | 10/20 | 0.61 |
| ▸ | HTR2C | P28335 | 5/20 | 0.58 |
| ▸ | HTR1A | P08908 | 4/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8569942 | 0.87 | HTR3E (0.65) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8563458 | 0.81 | HTR3E (0.73) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8572090 | 0.76 | HTR2C (0.73) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8563750 | 0.74 | HTR3E (1.00) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8878093 | 0.73 | OPRM1 (0.40) | HTR1A | |
| SCHEMBL8569563 | 0.73 | HTR3E (0.75) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8570434 | 0.72 | HTR2C (0.74) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8878905 | 0.72 | HTR2C (0.74) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8567791 | 0.72 | HTR3E (0.74) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL8569971 | 0.71 | HTR3E (0.73) | HTR3EHTR3BHTR3AHTR3DHTR3C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5599812-A | ANTISEROTONINE AGENTS | ADIR ET COMPAGNIE (FR) | 1997-02-04 | — | — | US | disclosed |