SCHEMBL8879

SCHEMBL8879

[c]1nnnc2ccccc12

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.35
LMNA P02545 1/20 0.33
HTT P42858 1/20 0.33
MAPT P10636 1/20 0.33
CYP1A2 P05177 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2140440 0.74 NQO2 (0.41) LMNAMAPT
SCHEMBL56536 0.70 MAPT (0.32) MAPT
SCHEMBL5778283 0.67
SCHEMBL2136821 0.67 LMNA (0.34) GPR3LMNAHTTCYP1A2CYP2C19
SCHEMBL3931666 0.67 TP53 (0.31)
SCHEMBL450208 0.67 GPR3 (0.35) GPR3MAPT
SCHEMBL395977 0.67 MAPT (0.50) GPR3LMNAHTTMAPTCYP1A2
SCHEMBL3188840 0.64 LMNA (0.48) GPR3LMNAHTTMAPTCYP1A2
Water SCHEMBL8456236 0.64 GPR3 (0.47) GPR3LMNAHTTMAPTCYP1A2
SCHEMBL3933590 0.63 CYP3A4 (0.40) GPR3LMNAHTTMAPTCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6233 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118290446-A Compound for inhibiting and degrading c-MYC and medical application thereof 西藏海思科制药有限公司 2024-07-05 CN claimed
CN-118271316-A Cycloheptenyl-containing derivative, pharmaceutical composition and pharmaceutical application thereof 西藏海思科制药有限公司 2024-07-02 CN claimed
CN-118255780-A Compound for inhibiting and degrading c-MYC and medical application thereof 西藏海思科制药有限公司 2024-06-28 CN claimed
EP-4385985-A1 HETEROCYCLIC DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL USE THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-06-19 EP claimed
CN-118206558-A Compound capable of inhibiting and degrading AuroraA, pharmaceutical composition and pharmaceutical application thereof 西藏海思科制药有限公司 2024-06-18 CN claimed
CN-118146224-A Nitrogen-containing tricyclic derivative and application thereof in medicine 西藏海思科制药有限公司 2024-06-07 CN claimed
US-20240174694-A1 PLURALITY OF HOST MATERIALS AND ORGANIC ELECTROLUMINESCENT DEVICE COMPRISING THE SAME DUPONT SPECIALTY MATERIALS KOREA LTD. (KR) 2024-05-30 US claimed
CN-117720517-A AR inhibitor, composition thereof and pharmaceutical application thereof 西藏海思科制药有限公司 2024-03-19 CN claimed
EP-4332100-A1 PHOSPHONYL DERIVATIVE, AND COMPOSITION AND PHARMACEUTICAL APPLICATION THEREOF Xizang Haisco Pharmaceutical Co., Ltd. (CN) 2024-03-06 EP claimed
EP-4326721-A1 SPIROCYCLIC IMIDAZOLIDINONES AND IMIDAZOLIDINEDIONES FOR TREATMENT OF LIGHT CHAIN AMYLOIDOSIS Protego Biopharma, Inc. (US) 2024-02-28 EP claimed
EP-0394194-B1 PROTECTED AMINO-ACIDS AND PROCESS FOR THEIR PREPARATION CALBIOCHEM-NOVABIOCHEM AG (CH) 1993-08-18 EP claimed
EP-0071819-B2 DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION BAYER AG (DE) 1992-06-10 EP claimed
EP-0119516-B1 3-AMINO-TETRAHYDRO-1,3-THIAZINE-2,4-DIONES, THEIR USE AND AGENTS CONTAINING THESE COMPOUNDS FOR THE TREATMENT OF THE SKIN Wella Aktiengesellschaft (DE) 1989-09-20 EP claimed
EP-0071819-B1 DIHYDROPYRIDINES WITH A POSITIVE INOTROPIC ACTIVITY, THEIR USE IN PHARMACEUTICAL PREPARATIONS, AND PROCESSES FOR THEIR PREPARATION BAYER AG (DE) 1987-04-22 EP claimed
US-4654339-A PROTECT THE SKIN AGAINST THE SUN, COLD AND AGING WELLA AKTIENGESELLSCHAFT (DE) 1987-03-31 US claimed
US-4643997-A PROTECTIVE COATINGS; SUNSCREEN AGENTS WELLA AKTIENGESELLSCHAFT (DE) 1987-02-17 US claimed
WO-1984003699-A1 3-AMINO-TETRAHYDRO-1,3-THIAZINE-2,4-DIONE, UTILISATION THEREOF AND SKIN TREATMENT PRODUCT CONTAINING SAID COMPOUNDS WELLA AG (DE) 1984-09-27 WO claimed
EP-0119516-A1 3-Amino-tetrahydro-1,3-thiazine-2,4-diones, their use and agents containing these compounds for the treatment of the skin Wella Aktiengesellschaft (DE) 1984-09-26 EP claimed
EP-0071819-A1 Dihydropyridines with a positive inotropic activity, their use in pharmaceutical preparations, and processes for their preparation BAYER AG (DE) 1983-02-16 EP claimed
EP-0042089-A2 4-Heterocylic substituted dihydropyridines, processes for preparing them, their therapeutical use and their preparation BAYER AG (DE) 1981-12-23 EP claimed