Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.52 |
| ▸ | GAA | P10253 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.48 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | HRH2 | P25021 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2226706 | 0.87 | GAA (0.55) | SMN1; SMN2GAAMAPTALDH1A1BCHE | |
| SCHEMBL8566291 | 0.81 | ACHE (0.47) | SMN1; SMN2GAAMAPTALDH1A1LMNA | |
| SCHEMBL16993891 | 0.81 | GAA (0.56) | SMN1; SMN2GAAMAPTALDH1A1BCHE | |
| SCHEMBL2275286 | 0.80 | SMN1; SMN2 (0.55) | SMN1; SMN2GAAMAPTALDH1A1BCHE | |
| SCHEMBL7832611 | 0.79 | GAA (0.54) | SMN1; SMN2GAAMAPTALDH1A1BCHE | |
| SCHEMBL1459682 | 0.77 | MAPT (0.57) | SMN1; SMN2GAAMAPTALDH1A1HRH2 | |
| SCHEMBL8609961 | 0.77 | SMN1; SMN2 (0.45) | SMN1; SMN2GAAMAPTALDH1A1BCHE | |
| SCHEMBL28057844 | 0.77 | MAPT (0.56) | SMN1; SMN2GAAMAPTALDH1A1LMNA | |
| SCHEMBL28826843 | 0.77 | MAPT (0.57) | SMN1; SMN2GAAMAPTALDH1A1HRH2 | |
| Potassium Ion SCHEMBL8582338 | 0.77 | ALDH1A1 (0.46) | SMN1; SMN2GAAMAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607936-A | USEFUL IN TREATMENT OF RESPIRATORY DISEASES | MERCK & CO., INC. (US) | 1997-03-04 | — | — | US | disclosed |