Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.35 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.35 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3259561 | 0.79 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL20853595 | 0.77 | TAS1R3 (0.35) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL503968 | 0.77 | AKR1B1 (0.41) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL6525902 | 0.74 | TSHR (0.35) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL701924 | 0.74 | CA2 (0.36) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL12650846 | 0.74 | TAS1R3 (0.38) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL15948146 | 0.74 | AKR1B1 (0.39) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| SCHEMBL15948192 | 0.73 | AKR1B1 (0.42) | TAS1R3TAS1R1TAS1R2TSHRHTT | |
| SCHEMBL31634838 | 0.72 | CASP1 (0.35) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 | |
| Potassium Ion SCHEMBL31634843 | 0.72 | CASP1 (0.35) | TAS1R3TAS1R1TAS1R2TSHRNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5643948-A | ANTIINFLAMMATORY, ANTICANCER | PROCYON PHARMACEUTICALS, INC. (US) | 1997-07-01 | — | — | US | disclosed |