Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | APEX1 | P27695 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 4/20 | 0.41 |
| ▸ | CA9 | Q16790 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL11858116 | 0.66 | TSHR (0.86) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL27400233 | 0.66 | TSHR (0.86) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL175823 | 0.66 | TSHR (1.00) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL5053781 | 0.66 | TSHR (1.00) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL2511919 | 0.66 | TSHR (1.00) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL1655 | 0.66 | TSHR (1.00) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL28861642 | 0.63 | TSHR (0.80) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL19665047 | 0.63 | TSHR (0.80) | TP53TSHRALDH1A1HPGDCA12 | |
| Terephthalic Acid SCHEMBL28535617 | 0.63 | TSHR (0.80) | TP53TSHRALDH1A1CA12CA9 | |
| Terephthalic Acid SCHEMBL4226573 | 0.63 | TSHR (0.80) | TP53TSHRALDH1A1HPGDCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650422-A | TREATMENT OF EMPHYSEMA, ARTHRITIS OR PANCREATITIS | SANOFI (FR) | 1997-07-22 | — | — | US | claimed |
| US-5236917-A | Respiratory system disorders, antiarthritic agents | STERLING WINTHROP INC. (US) | 1993-08-17 | — | — | US | claimed |