Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 3/20 | 0.44 |
| ▸ | HRH1 | P35367 | 2/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 5/20 | 0.41 |
| ▸ | UBE2N | P61088 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | SNCA | P37840 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8973707 | 0.83 | CYP2D6 (0.40) | CYP1A2CYP2D6 | |
| SCHEMBL4650418 | 0.80 | HTR2A (0.41) | HTR2AHRH1TAAR1MAOBUBE2N | |
| Hydrochloric Acid SCHEMBL182034 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8472312 | 0.72 | — | — | |
| SCHEMBL1893546 | 0.72 | SIGMAR1 (0.47) | HTR2ATAAR1MAOBSIGMAR1ADRA2B | |
| SCHEMBL26730248 | 0.72 | HTR2A (0.53) | HTR2AHRH1TAAR1UBE2NSIGMAR1 | |
| SCHEMBL6205916 | 0.70 | EPHX1 (0.59) | HTR2AHRH1TAAR1UBE2NSIGMAR1 | |
| Iodomethane SCHEMBL8880489 | 0.70 | — | — | |
| SCHEMBL10587652 | 0.70 | HTR2A (0.47) | HTR2AHRH1TAAR1MAOBUBE2N | |
| SCHEMBL15061219 | 0.70 | HTR2A (0.47) | HTR2AHRH1TAAR1UBE2NSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110275077-A1 | Oligonucleotide-Coated Affinity Membranes and Uses Thereof | JAMES WILLIAM | 2011-11-10 | — | — | US | claimed |
| US-20110275077-A1 | Oligonucleotide-Coated Affinity Membranes and Uses Thereof | JAMES WILLIAM | 2011-11-10 | — | — | US | disclosed |
| US-5354891-A | Rearrangement of an ortho-alkyl or -aryloxy-substituted hydroxamic acid in the presence of a base and a nitrile under mild conditions | FUJI PHOTO FILM CO., LTD. (JP) | 1994-10-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275077-A1 | Oligonucleotide-Coated Affinity Membranes and Uses Thereof | CD2BP2, CPSF6, CPSF1 | HTR2A 4595/4885HRH1 4651/4885TAAR1 4407/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.