Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP2A | P11388 | 2/20 | 0.39 |
| ▸ | TOP2B | Q02880 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8882384 | 0.86 | KDM4E (0.35) | KDM4EALDH1A1HTR2AHTR2CHTR2B | |
| SCHEMBL8882301 | 0.86 | TOP2A (0.37) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8884022 | 0.83 | KDM4E (0.33) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL8883002 | 0.79 | — | — | |
| SCHEMBL8882717 | 0.77 | TOP2A (0.41) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8881120 | 0.76 | ALDH1A1 (0.55) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8882157 | 0.75 | TOP2A (0.49) | TOP2ATOP2BKDM4EALDH1A1LMNA | |
| SCHEMBL8881681 | 0.74 | KDM4E (0.33) | KDM4EALDH1A1 | |
| SCHEMBL8882084 | 0.72 | LMNA (0.35) | KDM4EALDH1A1LMNACYP2C9HPGD | |
| SCHEMBL25052839 | 0.68 | HTR2C (0.49) | HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5663331-A | BACTERICIDES | IL-DONG PHARM. CO., LTD. (KR) | 1997-09-02 | — | — | US | disclosed |
| EP-0623136-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1994-11-09 | — | — | EP | disclosed |
| WO-1993015084-A1 | NOVEL CEPHALOSPORIN COMPOUNDS | IL-DONG PHARM. CO., LTD. (KR) | 1993-08-05 | — | — | WO | disclosed |
| WO-1993000359-A1 | MODIFIED PEPTIDES TRANSPORTABLE INTO THE CENTRAL NERVOUS SYSTEM | THE DU PONT MERCK PHARMACEUTICAL COMPANY (US) | 1993-01-07 | — | — | WO | disclosed |